Background/Objectives: As with many viral fusion proteins, the native conformation Slippers of SARS-CoV-2 Spike is metastable.Most COVID-19 vaccines utilize a stabilized Spike (Spike-2P) containing two proline substitutions, and subsequently, a further stabilized variant with four additional proline substitutions, Spike-6P, has been developed.In an

The article, based on the theoretical foundations of statistical management, considers the tasks, the solution of which should contribute to obtaining the information necessary for the effective functioning of the market segment.Its effective functioning means achieving a balance between supply and demand, which should result from the collection, p

Spinal interbody fusion is the most common surgery for treatment of disk degeneration, but the increased stress on adjacent level has been noted.Disk replacement has become an alternative strategy for dealing with problem of disk degeneration.Compressibility of an intact intervertebral disk is contributive to protect spinal structure, but certain m

The goal of this paper is to show that strong islands can be derived from the way derivation is linearized, as long as we assume that the derivation proceeds in a topdown fashion.To begin with, I will present one advantage of adopting a top-down approach regarding linearization issue: the Linear Correspondence Axiom (henceforth, LCA, Kayne 1994) ca